SCHEMBL13161683

SCHEMBL13161683

COc1c(C)cc(C(C)(C)c2cc(C)c(OC(=O)c3ccccc3)c(C)c2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.48
▸ TDP1 Q9NUW8 4/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ TSHR P16473 3/20 0.43
▸ LMNA P02545 2/20 0.42
▸ GAA P10253 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ SLC6A3 Q01959 1/20 0.41
▸ KMT2A Q03164 8/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ PKM P14618 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ CYP3A4 P08684 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ NPBWR1 P48145 1/20 0.39
▸ ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15493960 0.92 MAPT (0.50) MAPTTDP1L3MBTL1POLBALDH1A1
SCHEMBL13184038 0.88 MAPT (0.48) MAPTTDP1L3MBTL1TSHRLMNA
SCHEMBL16573870 0.87 KMT2A (0.39) MAPTL3MBTL1GAAALDH1A1KMT2A
SCHEMBL12346021 0.87 KMT2A (0.39) MAPTL3MBTL1GAAALDH1A1KMT2A
SCHEMBL13865060 0.87 ESR1 (0.39) MAPTTDP1L3MBTL1TSHRGAA
SCHEMBL14007584 0.87 ESR1 (0.39) MAPTTDP1L3MBTL1LMNAGAA
SCHEMBL13657589 0.86 TSHR (0.47) MAPTTDP1L3MBTL1TSHRLMNA
SCHEMBL12346020 0.86 ESR1 (0.41) MAPTL3MBTL1TSHRPOLBALDH1A1
SCHEMBL14580064 0.83 TDP1 (0.46) MAPTTDP1L3MBTL1TSHRLMNA
SCHEMBL140650 0.82 TSHR (0.45) MAPTTDP1L3MBTL1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343697-B2 Electrophotographic photoconductor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2013-01-01 — — US disclosed
US-7803507-B2 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2010-09-28 — — US disclosed
US-20090257777-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-10-15 — — US disclosed
US-7378212-B2 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-05-27 — — US disclosed
US-7183027-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2007-02-27 — — US disclosed
US-7183027-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2007-02-27 — — US disclosed
US-20070026334-A1 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2007-02-01 — — US disclosed
US-7160659-B2 Electrophotographic apparatus and process cartridge CANON KABUSHIKI KAISHA (JP) 2007-01-09 — — US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 — — US disclosed
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