SCHEMBL140650

SCHEMBL140650

COC(=O)c1ccc(C(=O)Oc2c(C)cc(C(C)(c3ccccc3)c3cc(C)c(OC)c(C)c3)cc2C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.45
▸ PPARA Q07869 1/20 0.42
▸ MAPT P10636 5/20 0.41
▸ L3MBTL1 Q9Y468 4/20 0.41
▸ RAB9A P51151 3/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ SENP8 Q96LD8 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41
▸ SENP6 Q9GZR1 1/20 0.41
▸ TDP1 Q9NUW8 3/20 0.41
▸ CA1 P00915 3/20 0.40
▸ CA2 P00918 3/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ SLC6A3 Q01959 1/20 0.40
▸ KMT2A Q03164 2/20 0.39
▸ EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13864904 0.94 TSHR (0.46) TSHRPPARAMAPTL3MBTL1RAB9A
SCHEMBL13865025 0.90 EGFR (0.46) TSHRPPARAMAPTL3MBTL1RAB9A
SCHEMBL13864965 0.86 TSHR (0.44) TSHRPPARAMAPTL3MBTL1RAB9A
SCHEMBL142008 0.84 MAPT (0.38) MAPTL3MBTL1RAB9ATDP1ALDH1A1
SCHEMBL13161683 0.82 MAPT (0.48) TSHRMAPTL3MBTL1TDP1KDM4E
SCHEMBL13864905 0.82 TSHR (0.47) TSHRPPARAMAPTL3MBTL1RAB9A
SCHEMBL16573861 0.81 TDP1 (0.50) TSHRMAPTRAB9ATDP1CA1
SCHEMBL13865009 0.81 SLC6A3 (0.40) TSHRPPARAMAPTCA1CA2
SCHEMBL15493960 0.81 MAPT (0.50) MAPTL3MBTL1TDP1ALDH1A1PKM
SCHEMBL14802304 0.80 ESR1 (0.42) TSHRPPARAMAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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