⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784776 | 0.70 | — | — | |
| SCHEMBL825623 | 0.70 | — | — | |
| SCHEMBL1019090 | 0.67 | — | — | |
| SCHEMBL1221950 | 0.67 | — | — | |
| SCHEMBL1899250 | 0.67 | — | — | |
| SCHEMBL1221949 | 0.67 | — | — | |
| SCHEMBL6054884 | 0.59 | — | — | |
| SCHEMBL28820 | 0.59 | — | — | |
| SCHEMBL2482004 | 0.59 | — | — | |
| SCHEMBL323342 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4112620-A1 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University of Bristol (GB) | 2023-01-04 | — | — | EP | claimed |
| US-20200172544-A1 | COMPOUNDS | THE UNIVERSITY OF BRISTOL (GB) | 2020-06-04 | — | — | US | claimed |
| EP-3500572-A2 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University Of Bristol (GB) | 2019-06-26 | — | — | EP | claimed |
| WO-2018033742-A2 | COMPOUNDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-02-22 | — | — | WO | claimed |
| US-11905287-B2 | 4-substitued cytisine analogues | THE UNIVERSITY OF BRISTOL (GB) | 2024-02-20 | — | — | US | disclosed |
| US-20230203038-A1 | 4-SUBSTITUED CYTISINE ANALOGUES | THE UNIVERSITY OF BRISTOL (GB) | 2023-06-29 | — | — | US | disclosed |
| US-11667638-B2 | 4-substitued cytisine analogues | THE UNIVERSITY OF BRISTOL | 2023-06-06 | — | — | US | disclosed |
| EP-4112620-A1 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University of Bristol (GB) | 2023-01-04 | — | — | EP | disclosed |
| US-20200172544-A1 | COMPOUNDS | THE UNIVERSITY OF BRISTOL (GB) | 2020-06-04 | — | — | US | disclosed |
| CN-110505874-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | DOW AGROSCIENCES LLC | 2019-11-26 | — | — | CN | disclosed |
| CN-106458860-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-26 | — | — | CN | disclosed |
| EP-3500572-A2 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University Of Bristol (GB) | 2019-06-26 | — | — | EP | disclosed |
| EP-1710234-A1 | MALONONITRILE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2006-10-11 | — | — | EP | disclosed |
| EP-1704143-A1 | MALONONITRILE COMPOUND AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| EP-1697311-A1 | NITRILE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
| CN-1233685-C | Fluorinated cycloolefin polymer, cycloolefin monomer thereof, preparation method of polymer and application of polymer | MITSUI CHEMICALS INC (JP) | 2005-12-28 | — | — | CN | disclosed |
| WO-2005068432-A1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-28 | — | — | WO | disclosed |
| WO-2005063694-A1 | NITRILE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-14 | — | — | WO | disclosed |
| CN-1462286-A | Fluorinated cycloolefin polymers, its cycloolefin monomers processes for preparation of polymers thereof and use of the same | MITSUI CHEMICALS INC (JP) | 2003-12-17 | — | — | CN | disclosed |
| US-3764705-A | 1-BROMO2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER AS AN INHALATION ANESTHETIC | BOC, INC., A DE CORP. | 1973-10-09 | — | — | US | disclosed |