SCHEMBL323342

SCHEMBL323342

F[CH]C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549735 0.67
SCHEMBL17311848 0.67
SCHEMBL2330856 0.67
SCHEMBL9405666 0.67
SCHEMBL620237 0.67
SCHEMBL26566 0.64
SCHEMBL775790 0.64
SCHEMBL21831190 0.64
SCHEMBL16755599 0.64
SCHEMBL25830 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572210-B (1,2,2,2-tetrafluoroethyl) arene derivative and preparation method and application thereof 暨南大学 2023-03-21 CN claimed
US-20210253533-A1 DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS BAYER AG (DE) 2021-08-19 US claimed
CN-113195462-A Microbicidal oxadiazole derivatives 先正达农作物保护股份公司 2021-07-30 CN claimed
EP-3416959-B1 PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-05-12 EP claimed
US-20210114990-A1 DISUBSTITUTED 3-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION VIA ACYLATION OF ENOLATES BAYER AG (DE) 2021-04-22 US claimed
EP-3807250-A1 DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS Bayer Aktiengesellschaft (DE) 2021-04-21 EP claimed
EP-3807249-A1 DISUBSTITUTED 3-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION VIA ACYLATION OF ENOLATES Bayer Aktiengesellschaft (DE) 2021-04-21 EP claimed
CN-112351972-A Disubstituted 5(3) -pyrazole carboxylic acid esters and methods of making same from enol esters and Fluoroalkylamino (FAR) reagents 拜耳公司 2021-02-09 CN claimed
CN-112334449-A Disubstituted 3-pyrazole carboxylic esters and process for preparing them by acylation of enol esters 拜耳公司 2021-02-05 CN claimed
EP-3169674-B1 ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-01-20 EP claimed
WO-2003050096-A1 THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2003-06-19 WO claimed
WO-2001017977-A1 1,3,5-TRIAZINES AS HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-03-15 WO claimed
EP-0694526-B1 Process for preparation of fluorinated beta-keto ester ROHM & HAAS (US) 1998-10-07 EP claimed
US-5493025-A Process for preparation of fluorinated beta-keto ester ROHM AND HAAS COMPANY (US) 1996-02-20 US claimed
EP-0694526-A1 Process for preparation of fluorinated beta-keto ester ROHM AND HAAS COMPANY (US) 1996-01-31 EP claimed
EP-0482938-A1 Synthesis of fluorinated ethers RHONE-POULENC CHEMICALS LIMITED (GB) 1992-04-29 EP claimed
US-5068241-A Pesticidal substituted pyrazoline derivatives, compositions and use BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US claimed
EP-0443162-A1 Substituted pyrazoline derivatives BAYER AG (DE) 1991-08-28 EP claimed
EP-0158594-B1 PROCESS FOR THE PREPARATION OF FLUOROALKOXY-AMINO-PYRIMIDINES CIBA-GEIGY AG (CH) 1988-02-10 EP claimed
US-4542216-A FLUOROALKYLATION OF A THIOPYRAMIDINE CIBA GEIGY CORPORATION (US) 1985-09-17 US claimed