Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165761 | 0.95 | BDKRB1 (0.33) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13165776 | 0.93 | OPRL1 (0.35) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13165725 | 0.92 | CARM1 (0.34) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13165719 | 0.92 | SCN9A (0.36) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13165593 | 0.91 | MAPT (0.35) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13165766 | 0.91 | MAPT (0.33) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13166162 | 0.90 | HPGD (0.34) | MAPTOPRL1UBE2MDCUN1D1 | |
| SCHEMBL13166112 | 0.90 | OPRL1 (0.38) | OPRL1CCR2UBE2MDCUN1D1 | |
| SCHEMBL13165790 | 0.89 | MAPT (0.34) | MAPTOPRL1CCR2SCN9ACARM1 | |
| SCHEMBL13166420 | 0.88 | MAPT (0.41) | MAPTKMT2APOLBMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |