Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165764 | 0.95 | UBE2M (0.33) | HPGDHTTOPRL1UBE2MDCUN1D1 | |
| SCHEMBL13165776 | 0.92 | OPRL1 (0.35) | OPRL1UBE2MDCUN1D1MAPTEPHX2 | |
| SCHEMBL13166401 | 0.92 | POLB (0.35) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13165587 | 0.90 | MAPT (0.32) | OPRL1MAPT | |
| SCHEMBL13165790 | 0.90 | MAPT (0.34) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13166402 | 0.90 | MAPT (0.34) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13165725 | 0.90 | CARM1 (0.34) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13165719 | 0.90 | SCN9A (0.36) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13165593 | 0.89 | MAPT (0.35) | OPRL1UBE2MDCUN1D1MAPT | |
| SCHEMBL13165644 | 0.89 | ALDH1A1 (0.40) | MAPTALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |