Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13167675 | 0.92 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2918295 | 0.92 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL2915745 | 0.92 | CYP3A4 (0.38) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL2911986 | 0.91 | CYP3A4 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2915694 | 0.87 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2919213 | 0.87 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL13167677 | 0.84 | NPC1 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL14141937 | 0.84 | MAP1LC3B (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL14294711 | 0.84 | MAP1LC3B (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL2913793 | 0.84 | NPC1 (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | ZHANG HESHENG | 2010-09-23 | — | — | US | disclosed |
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | ZHANG HESHENG | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240651-A1 | WATER-SOLUBLE THALIDOMIDE DERIVATIVES | CCNH, CBR1, CBR3 | CYP3A4 958/4885CYP2D6 601/4885CYP2C9 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.