Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | PRKCG | P05129 | 2/20 | 0.47 |
| ▸ | PRKCB | P05771 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKCH | P24723 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1317693 | 1.00 | DNM1 (0.48) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1318941 | 1.00 | DNM1 (0.48) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1319650 | 1.00 | DNM1 (0.48) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1316934 | 0.93 | DNM1 (0.50) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1318826 | 0.93 | DNM1 (0.50) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1318845 | 0.93 | DNM1 (0.50) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Iodide SCHEMBL1316812 | 0.93 | DNM1 (0.50) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL12120358 | 0.91 | PRKD3 (0.44) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL12120349 | 0.91 | PRKD3 (0.44) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL12120354 | 0.91 | PRKD3 (0.44) | DNM1PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269652-A1 | GEMINI SURFACTANTS | ST. FRANCIS XAVIER UNIVERSITY (CA) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269652-A1 | GEMINI SURFACTANTS | SGMS1, DEGS1, GMNN | DNM1 2074/4885PRKD3 3017/4885PRKCG 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.