Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.87 |
| ▸ | ITGAV | P06756 | 17/20 | 0.87 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.87 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.87 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.87 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176461 | 0.93 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176963 | 0.93 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176936 | 0.93 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7264806 | 0.90 | ITGB3 (0.94) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7264797 | 0.90 | ITGB3 (0.94) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL13170294 | 0.83 | ITGB3 (0.74) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176984 | 0.83 | ITGB3 (0.80) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176988 | 0.83 | ITGB3 (0.80) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6773175 | 0.82 | ITGB3 (0.80) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6177908 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |