Acetonitrile

Acetonitrile

SCHEMBL131712

CC#N.CN1CCOCC1.COS(=O)(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of Acetonitrile. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TSHR P16473 6/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
GAA P10253 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
USP2 O75604 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634165 0.91 CA12 (0.44) CA12CA7CA14TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL2374802 0.89 CA12 (0.43) CA12CA7CA14TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL7120564 0.89 CA12 (0.43) CA12CA7CA14TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL27834913 0.85 CA12 (0.40) CA12CA7CA14TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL14740092 0.84 CA12 (0.39) CA12CA7CA14TSHRSMN1; SMN2
Acetonitrile SCHEMBL4389482 0.83 TSHR (0.37) CA12CA7CA14TSHRSMN1; SMN2
Acetamide SCHEMBL6559564 0.82 SMN1; SMN2 (0.38) CA12CA7CA14TSHRSMN1; SMN2
N-Methylpiperidine SCHEMBL8662116 0.81
Acetonitrile SCHEMBL304666 0.80 CA12 (0.36) CA12CA7CA14TSHRSMN1; SMN2
SCHEMBL28051043 0.79 CA12 (0.44) CA12CA7CA14TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1261686-B1 MULTIPHASE MOULDED DETERGENT BODIES WITH NON-PRESSED PARTS HENKEL AG & CO KGAA (DE) 2016-06-15 EP claimed
EP-1157090-B2 METHOD OF PREPARING MULTI-PHASE MOULDED DETERGENT AND/OR CLEANING AGENT ARTICLES HENKEL AG & CO KGAA (DE) 2014-08-27 EP claimed
EP-1299517-B2 DISHWASHER AGENT WITH ADDITIONAL USES HENKEL AG & CO KGAA (DE) 2010-05-19 EP claimed
EP-1678287-B1 DISPENSER CONTAINING LIQUID BLEACHING COMPOSITION RECKITT BENCKISER UK LTD (GB) 2007-08-29 EP claimed
EP-1678287-A1 LIQUID BLEACHING COMPOSITION Reckitt Benckiser (UK) LIMITED (GB) 2006-07-12 EP claimed
EP-1103599-B1 Particle form rinse aid and dishwasher detergent composition HENKEL KGAA (DE) 2006-03-08 EP claimed
EP-1157090-B1 METHOD OF PREPARING MULTI-PHASE MOULDED DETERGENT AND/OR CLEANING AGENT ARTICLES HENKEL KGAA (DE) 2005-09-21 EP claimed
EP-1299517-B1 DISHWASHER AGENT WITH ADDITIONAL USES HENKEL KGAA (DE) 2005-08-31 EP claimed
WO-2005042686-A1 LIQUID BLEACHING COMPOSITION RECKITT BENCKISER (UK) LIMITED (GB) 2005-05-12 WO claimed
EP-1141191-B1 PHOSPHATE COMPOUNDS HENKEL KGAA (DE) 2005-03-09 EP claimed
CN-1345305-A Method of preparing granular N-alkyl-ammonium acetonitrile salts BASF AG (DE) 2002-04-17 CN claimed
US-20020006890-A1 Multiphase laundry detergent and cleaning product shaped bodies having noncompressed parts HENKEL AG & CO. KGAA (DE) 2002-01-17 US claimed
WO-2002004588-A1 DISHWASHER AGENT WITH ADDITIONAL USES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-01-17 WO claimed
EP-1165497-A1 METHOD OF PREPARING GRANULAR N-ALKYL-AMMONIUM ACETONITRILE SALTS BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP claimed
EP-0941299-B1 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AG (DE) 2001-08-29 EP claimed
EP-1103599-A1 Particle form rinse aid and dishwasher detergent composition Henkel Kommanditgesellschaft auf Aktien (DE) 2001-05-30 EP claimed
WO-2000058273-A1 METHOD OF PREPARING GRANULAR N-ALKYL-AMMONIUM ACETONITRILE SALTS BASF AKTIENGESELLSCHAFT (DE) 2000-10-05 WO claimed
EP-0941299-A2 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-15 EP claimed
WO-1998023718-A2 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-06-04 WO claimed
US-5739327-A OXYGEN BLEACHES OF NITRILE BONDED TO QUATERNARY NITROGEN THE CLOROX COMPANY (US) 1998-04-14 US claimed