Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634165 | 0.91 | CA12 (0.44) | SMN1; SMN2CA12CA7CA14KDM4E | |
| Acetonitrile SCHEMBL131712 | 0.82 | CA12 (0.38) | SMN1; SMN2CA12CA7CA14KDM4E | |
| SCHEMBL11070402 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2CA12CA7CA14TSHR | |
| SCHEMBL28051043 | 0.79 | CA12 (0.44) | SMN1; SMN2CA12CA7CA14TSHR | |
| Sulfamate SCHEMBL27744770 | 0.78 | CA7 (0.48) | SMN1; SMN2CA12CA7CA14KDM4E | |
| Sulfuric Acid SCHEMBL21616458 | 0.78 | CA12 (0.52) | SMN1; SMN2CA12CA7CA14TSHR | |
| Sulfuric Acid SCHEMBL28051044 | 0.78 | CA12 (0.52) | SMN1; SMN2CA12CA7CA14TSHR | |
| SCHEMBL3806089 | 0.76 | CA12 (0.50) | SMN1; SMN2CA12CA7CA14TSHR | |
| Acetamide SCHEMBL6843069 | 0.76 | BLM (0.50) | CA7CA14KDM4ETSHRALDH1A1 | |
| SCHEMBL9442610 | 0.74 | KDM4E (0.45) | SMN1; SMN2CA12CA7CA14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036070-B1 | N-ALKYL AMMONIUM ACETONITRILE SALTS, METHODS THEREFOR AND COMPOSITIONS THEREWITH | CLOROX CO (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0944609-B1 | PROCESS FOR PREPARING N-ALKYL AMMONIUM ACETONITRILE COMPOUNDS | CLOROX CO (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0951438-A4 | GRANULAR N-ALKYL AMMONIUM ACETONITRILE COMPOSITIONS | CLOROX CO (US) | 2002-08-14 | — | — | EP | disclosed |
| CN-1083444-C | Process for preparing N-alkyl ammonium acetonitrile compounds | CLOROX CO (US) | 2002-04-24 | — | — | CN | disclosed |
| EP-0948455-A4 | MIXED PEROXYGEN ACTIVATOR COMPOSITIONS | CLOROX CO (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-1036070-A4 | N-ALKYL AMMONIUM ACETONITRILE SALTS, METHODS THEREFOR AND COMPOSITIONS THEREWITH | CLOROX CO (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-1036070-A1 | N-ALKYL AMMONIUM ACETONITRILE SALTS, METHODS THEREFOR AND COMPOSITIONS THEREWITH | The Clorox Company (US) | 2000-09-20 | — | — | EP | disclosed |
| CN-1248969-A | Process for preparing N-alkyl ammonium acetonitrile compounds | CLOROX CO (US) | 2000-03-29 | — | — | CN | disclosed |
| EP-0951438-A1 | GRANULAR N-ALKYL AMMONIUM ACETONITRILE COMPOSITIONS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-27 | — | — | EP | disclosed |
| EP-0948455-A1 | MIXED PEROXYGEN ACTIVATOR COMPOSITIONS | The Clorox Company (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998023534-A1 | MIXED PEROXYGEN ACTIVATOR COMPOSITIONS | THE CLOROX COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998023531-A1 | GRANULAR N-ALKYL AMMONIUM ACETONITRILE COMPOSITIONS | THE CLOROX COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998023602-A1 | N-ALKYL AMMONIUM ACETONITRILE SALTS, METHODS THEREFOR AND COMPOSITIONS THEREWITH | THE CLOROX COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |