Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 4/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SDHA | P31040 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101170 | 0.89 | MAOA (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL13367796 | 0.80 | MAOA (0.41) | MAOAF10CALML3MAOBCYP3A4 | |
| SCHEMBL13368025 | 0.76 | MAOA (0.46) | MAOAF10CALML3MAOBLMNA | |
| SCHEMBL10152836 | 0.76 | CALML3 (0.48) | MAOACALML3MAOBCYP2C19CYP2C9 | |
| SCHEMBL10152840 | 0.76 | MAOA (0.39) | MAOACALML3CYP2E1MAOBCYP2C19 | |
| SCHEMBL13367993 | 0.74 | MAOA (0.41) | MAOAF10CALML3MAOBLMNA | |
| SCHEMBL10151605 | 0.73 | MAOA (0.51) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10152835 | 0.73 | MAOB (0.42) | MAOAF10CALML3MAOBLMNA | |
| SCHEMBL13589343 | 0.72 | MAOA (0.36) | MAOACALML3MAOBCYP2C19CYP2C9 | |
| SCHEMBL10151606 | 0.72 | MAOA (0.41) | MAOAF10CALML3MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233484-A2 | Oxazolidinone derivatives having a 7-membered heterocyclic ring | Research Foundation Itsuu Laboratory (JP) | 2010-09-29 | — | — | EP | disclosed |
| EP-2208729-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation Itsuu Laboratory (JP) | 2010-07-21 | — | — | EP | disclosed |