Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 9/20 | 0.52 |
| ▸ | FEN1 | P39748 | 9/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | DNASE1 | P24855 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174752 | 0.90 | KMT2A (0.51) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13174725 | 0.88 | KMT2A (0.49) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13296823 | 0.88 | ERCC1 (0.48) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13174750 | 0.87 | KMT2A (0.48) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13211359 | 0.87 | ERCC1 (0.54) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13296836 | 0.86 | KMT2A (0.47) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13296832 | 0.85 | KMT2A (0.47) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13174891 | 0.83 | ERCC1 (0.50) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13174731 | 0.82 | MAPT (0.54) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL13175048 | 0.81 | ERCC1 (0.48) | ERCC1FEN1ERCC4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223921-A1 | 2-Thiophen-2-yl-oxazole, 2-Thiophen-2-yl-thiazole and 2-Thiophen-2-yl-1H-imidazole derivatives as antiviral agents | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2010-09-01 | — | — | EP | disclosed |
| EP-1889843-A1 | BISHETEROCYCLE TANDEM COMPOUNDS USEFUL AS ANTIVIRAL AGENTS, THE USES THEREOF AND THE COMPOSITIONS COMPRISING SUCH COMPOUNDS | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2008-02-20 | — | — | EP | disclosed |