Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.70 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175171 | 0.90 | LTB4R (0.64) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL200665 | 0.90 | LTB4R (0.86) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13175194 | 0.90 | LTB4R (0.70) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13174996 | 0.90 | LTB4R (0.56) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL201167 | 0.89 | LTB4R (0.87) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690426 | 0.89 | LTB4R (0.65) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL200956 | 0.89 | LTB4R (0.74) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13175183 | 0.89 | LTB4R (0.69) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL200844 | 0.88 | LTB4R (0.78) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL200794 | 0.88 | LTB4R (0.74) | LTB4RLTB4R2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108856-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-30 | — | — | WO | disclosed |