Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | TACR3 | P29371 | 4/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175478 | 0.91 | TACR3 (0.56) | AKR1C3TACR3LMNAKDM5BPDK1 | |
| SCHEMBL13175689 | 0.90 | AKR1C3 (0.50) | AKR1C3TACR3LMNAKDM5B | |
| SCHEMBL13175692 | 0.88 | AKR1C3 (0.50) | AKR1C3TACR3LMNAKDM5BPDK1 | |
| SCHEMBL13175454 | 0.84 | KDM5B (0.56) | AKR1C3TACR3LMNAKDM5BPDK1 | |
| SCHEMBL13175618 | 0.84 | AKR1C3 (0.59) | AKR1C3TACR3KDM5B | |
| SCHEMBL13175475 | 0.84 | AKR1C3 (0.47) | AKR1C3TACR3LMNAKDM5BPDK1 | |
| SCHEMBL13175632 | 0.83 | AKR1C3 (0.59) | AKR1C3TACR3LMNAKDM5BMAPT | |
| SCHEMBL13175612 | 0.83 | TACR3 (0.53) | AKR1C3TACR3LMNAKDM5BMAPT | |
| SCHEMBL13175738 | 0.83 | AKR1C3 (0.50) | AKR1C3TACR3LMNAKDM5BPDK1 | |
| SCHEMBL13175498 | 0.83 | AKR1C3 (0.46) | AKR1C3TACR3RORCLMNAKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |