Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.46 |
| ▸ | TACR3 | P29371 | 4/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175454 | 0.91 | KDM5B (0.56) | AKR1C3KDM5BTACR3PDK1PDK2 | |
| SCHEMBL13175489 | 0.88 | AKR1C3 (0.48) | AKR1C3KDM5BTACR3PDK1PDK2 | |
| SCHEMBL13175878 | 0.87 | MAPT (0.49) | AKR1C3KDM5BTACR3PDK1PDK2 | |
| SCHEMBL13175738 | 0.87 | AKR1C3 (0.50) | AKR1C3KDM5BTACR3PDK1PDK2 | |
| SCHEMBL13175618 | 0.86 | AKR1C3 (0.59) | AKR1C3KDM5BTACR3 | |
| SCHEMBL13175612 | 0.85 | TACR3 (0.53) | AKR1C3KDM5BTACR3LMNAMAPT | |
| SCHEMBL13175632 | 0.85 | AKR1C3 (0.59) | AKR1C3KDM5BTACR3LMNAMAPT | |
| SCHEMBL13175478 | 0.85 | TACR3 (0.56) | AKR1C3KDM5BTACR3PDK1PDK2 | |
| SCHEMBL13175711 | 0.84 | AKR1C3 (0.54) | AKR1C3KDM5BTACR3LMNAALPL | |
| SCHEMBL13175620 | 0.84 | TACR3 (0.58) | AKR1C3KDM5BTACR3MAPTALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |