Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175632 | 0.84 | AKR1C3 (0.59) | ALPLMAPTRAB9AAKR1C3TACR3 | |
| SCHEMBL13175617 | 0.84 | AKR1C3 (0.44) | KDM4EMAPTNPC1RAB9AAKR1C3 | |
| SCHEMBL13175715 | 0.83 | AKR1C3 (0.50) | ALPLMAPTAKR1C3TACR3LMNA | |
| SCHEMBL13175738 | 0.83 | AKR1C3 (0.50) | MAPTAKR1C3TACR3LMNAKDM5B | |
| SCHEMBL13175455 | 0.83 | AKR1C3 (0.57) | AKR1C3TACR3LMNAKDM5BMEN1 | |
| SCHEMBL13175620 | 0.83 | TACR3 (0.58) | ALPLMAPTAKR1C3TACR3KDM5B | |
| SCHEMBL13175695 | 0.83 | LMNA (0.59) | MAPTAKR1C3TACR3LMNAKDM5B | |
| SCHEMBL13175454 | 0.83 | KDM5B (0.56) | ALPLMAPTAKR1C3TACR3LMNA | |
| SCHEMBL13175618 | 0.83 | AKR1C3 (0.59) | AKR1C3TACR3KDM5BMEN1KMT2A | |
| SCHEMBL13175696 | 0.83 | TACR3 (0.52) | ALPLMAPTAKR1C3TACR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |