Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161005 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL2113005 | 0.83 | PTGDR2 (0.64) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL3032640 | 0.82 | HPGD (0.56) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL16220554 | 0.79 | MEN1 (0.59) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL5742045 | 0.78 | MEN1 (0.57) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL2096772 | 0.78 | KMT2A (0.53) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL293026 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL891407 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2AHPGDMAPT | |
| SCHEMBL16263507 | 0.77 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL12883303 | 0.77 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |