Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320418 | 0.87 | PTGDR2 (0.66) | PTGDR2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL16220554 | 0.85 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL3064143 | 0.85 | TSHR (0.70) | PTGDR2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL197583 | 0.84 | PPARD (0.55) | PTGDR2PPARGPPARDPPARATDP1 | |
| SCHEMBL2717225 | 0.84 | PTGDR2 (0.62) | PTGDR2SMN1; SMN2KDM4ETDP1TSHR | |
| SCHEMBL5742045 | 0.84 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL3385737 | 0.84 | PPARD (0.69) | PPARGPPARDPPARA | |
| SCHEMBL13176926 | 0.83 | SMN1; SMN2 (0.53) | PTGDR2MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17908113 | 0.82 | PPARD (0.52) | PTGDR2MEN1KMT2APPARGPPARD | |
| SCHEMBL2823002 | 0.82 | PPARD (0.52) | PTGDR2SMN1; SMN2KDM4EPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971222-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007059066-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| US-20070110844-A1 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. | 2007-05-17 | — | — | US | claimed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | claimed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | claimed |
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) | 2024-03-19 | — | — | US | disclosed |
| EP-2388003-B1 | Colchicine derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |
| US-20210206777-A1 | LYCORINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) | 2021-07-08 | — | — | US | disclosed |
| EP-3207929-B1 | COLCHICINE DERIVATIVES FOR THE TREATMENT OF CANCER | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-05-26 | — | — | EP | disclosed |
| CN-110759927-B | Lycorine derivatives, pharmaceutical composition and application thereof | 山东达因海洋生物制药股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-110759927-A | Lycorine derivatives, pharmaceutical composition and application thereof | 山东达因海洋生物制药股份有限公司 | 2020-02-07 | — | — | CN | disclosed |
| WO-2020019357-A1 | LYCORINE DERIVATIVES, PHARMACEUTICAL COMPOSITE THEREOF AND USAGE THEREFOR | 山东达因海洋生物制药股份有限公司 | 2020-01-30 | — | — | WO | disclosed |
| EP-0250583-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. Nattermann & Cie. GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0231765-A1 | Use of membrane modulators and products comprising such membrane modulators | A. Nattermann & Cie. GmbH (DE) | 1987-08-12 | — | — | EP | disclosed |
| WO-1987004048-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. NATTERMANN & CIE GMBH (DE) | 1987-07-16 | — | — | WO | disclosed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | disclosed |
| EP-0068295-B1 | A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0068295-A1 | A new herbicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4090862-A | Novel phenoxycarboxylic acid aryloxy(thio)carbonylaminomethyl esters and their use for regulating plant growth | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-23 | — | — | US | disclosed |
| US-3985559-A | Toner powder for electrostatic images | OCE-VAN DER GRINTEN N.V. (NL) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | LCT, LARP7, LASP1 | PTGDR2 4342/4885MEN1 3036/4885KMT2A 3991/4885 |
| US-20210206777-A1 | LYCORINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | LARP7, LARP1, LASP1 | PTGDR2 4406/4885MEN1 3232/4885KMT2A 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.