Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.65 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11781277 | 0.92 | MAPT (0.56) | MAPTL3MBTL1SRD5A2STSPDPK1 | |
| SCHEMBL7129800 | 0.89 | MAPT (0.80) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| SCHEMBL24800 | 0.85 | MAPT (0.73) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| SCHEMBL8033816 | 0.83 | SRD5A2 (0.89) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| SCHEMBL5260372 | 0.83 | SRD5A2 (0.89) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| Bicarbonate SCHEMBL28984888 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| SCHEMBL4282905 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| Water SCHEMBL20527670 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| Hydrochloric Acid SCHEMBL27315608 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2STSRAB9A | |
| Water SCHEMBL9243001 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2STSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853423-B2 | Indane estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130137746-A1 | INDANE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| EP-1501819-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-09-15 | — | — | EP | disclosed |
| CN-1303851-A | Synthesis method of idocifen | SHANGHAI RES INST OF PHARMACEU (CN) | 2001-07-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137746-A1 | INDANE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GPER1, ESR2, ESR1 | MAPT 2559/4885L3MBTL1 4840/4885SRD5A2 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.