SCHEMBL7129800

SCHEMBL7129800

O=C(Cc1ccccc1)c1ccc(C(=O)Cc2ccccc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.80
L3MBTL1 Q9Y468 1/20 0.80
SRD5A2 P31213 2/20 0.77
STS P08842 1/20 0.62
CES1 P23141 2/20 0.61
CES2 O00748 1/20 0.61
AKR1B1 P15121 1/20 0.61
RAB9A P51151 3/20 0.58
PLAU P00749 2/20 0.58
KDM4E B2RXH2 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NPC1 O15118 2/20 0.58
S1PR5 Q9H228 1/20 0.57
GAA P10253 1/20 0.56
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
MAPK1 P28482 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24800 0.95 MAPT (0.73) MAPTL3MBTL1SRD5A2STSCES1
SCHEMBL8033816 0.93 SRD5A2 (0.89) MAPTL3MBTL1SRD5A2STSCES1
SCHEMBL5260372 0.93 SRD5A2 (0.89) MAPTL3MBTL1SRD5A2STSCES1
Hydrochloric Acid SCHEMBL27315608 0.93 MAPT (0.70) MAPTL3MBTL1SRD5A2STSCES1
Water SCHEMBL20527670 0.93 MAPT (0.70) MAPTL3MBTL1SRD5A2STSCES1
Bicarbonate SCHEMBL28984888 0.93 MAPT (0.70) MAPTL3MBTL1SRD5A2STSCES1
Water SCHEMBL9243001 0.93 MAPT (0.70) MAPTL3MBTL1SRD5A2STSCES1
SCHEMBL4282905 0.93 MAPT (0.70) MAPTL3MBTL1SRD5A2STSCES1
SCHEMBL11635179 0.91 L3MBTL1 (0.69) MAPTL3MBTL1SRD5A2STSCES1
SCHEMBL1515907 0.91 SRD5A2 (0.85) MAPTL3MBTL1SRD5A2STSCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082806-A PREPARATION OF TETRAKETONES WRIGHT STATE UNIVERSITY (US) 1978-04-04 US claimed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US claimed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
WO-2003042148-A3 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO KK (JP) 2003-10-16 WO disclosed
JP-2003192628-A METHOD FOR PRODUCING BISBENZYL COMPOUND SHOWA DENKO KK 2003-07-09 JP disclosed
JP-2003192629-A METHOD FOR PRODUCING BIS(PHENYLACETYL)BENZENE SHOWA DENKO KK 2003-07-09 JP disclosed
JP-2003171332-A METHOD FOR PRODUCING BISBENZYL COMPOUND SHOWA DENKO KK 2003-06-20 JP disclosed
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed
EP-0444142-B1 POLYQUINOLINE COPOLYMERS HITACHI CHEMICAL CO LTD (JP) 2000-03-29 EP disclosed
US-5723573-A ACETYLENIC END GROUPS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-03-03 US disclosed
US-5117062-A Aromatic tertiary amines, enamines, deoxybenzoins and benzils HAY ALLAN S (CA) 1992-05-26 US disclosed
EP-0444142-A4 POLYQUINOLINE COPOLYMERS 1991-10-16 EP disclosed
EP-0444142-A1 POLYQUINOLINE COPOLYMERS HITACHI CHEMICAL CO., LTD. (JP) 1991-09-04 EP disclosed
US-5017677-A Molding materials, laminates, adhesives, films and fibers COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1991-05-21 US disclosed
WO-1990005754-A1 POLYQUINOLINE COPOLYMERS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1990-05-31 WO disclosed
US-4082806-A PREPARATION OF TETRAKETONES WRIGHT STATE UNIVERSITY (US) 1978-04-04 US disclosed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US disclosed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US disclosed
US-3935239-A Process for producing aromatic α-diketones NEILAND OYAR YANOVICH 1976-01-27 US disclosed