Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348236 | 0.83 | HDAC1 (0.74) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL19609271 | 0.82 | HDAC1 (0.66) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL8348228 | 0.79 | HDAC1 (0.71) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL1065917 | 0.78 | HDAC1 (1.00) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL8348764 | 0.78 | HDAC1 (1.00) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL1065916 | 0.78 | HDAC1 (1.00) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL17483912 | 0.77 | HDAC1 (0.68) | HDAC1KDM1AMAOAHDAC2 | |
| SCHEMBL1065134 | 0.77 | HDAC1 (0.80) | HDAC1HDAC2 | |
| SCHEMBL1065131 | 0.77 | HDAC1 (0.80) | HDAC1HDAC2 | |
| SCHEMBL2732582 | 0.77 | HDAC1 (0.80) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795315-B2 | N-(2-amino-phenyl)-amide derivatives | HOFFMAN-LA ROCHE INC. (US) | 2010-09-14 | — | — | US | disclosed |