Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | EP300 | Q09472 | 1/20 | 0.60 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640602 | 0.85 | HDAC1 (0.66) | HDAC1HDAC2 | |
| SCHEMBL8348236 | 0.85 | HDAC1 (0.74) | HDAC1HDAC2KDM1AMAOAHDAC4 | |
| SCHEMBL3228583 | 0.85 | EGFR (0.71) | HDAC1HDAC2MAOAHDAC4EP300 | |
| SCHEMBL3228591 | 0.85 | EGFR (0.71) | HDAC1HDAC2MAOAHDAC4EP300 | |
| SCHEMBL7978520 | 0.84 | HDAC1 (0.64) | HDAC1HDAC2 | |
| SCHEMBL1065917 | 0.83 | HDAC1 (1.00) | HDAC1HDAC2KDM1AMAOAHDAC4 | |
| SCHEMBL1065916 | 0.83 | HDAC1 (1.00) | HDAC1HDAC2KDM1AMAOAHDAC4 | |
| SCHEMBL8348764 | 0.83 | HDAC1 (1.00) | HDAC1HDAC2KDM1AMAOAHDAC4 | |
| SCHEMBL4536420 | 0.83 | TRPA1 (0.68) | HDAC1HDAC2HDAC4MEF2D | |
| SCHEMBL4536422 | 0.83 | TRPA1 (0.68) | HDAC1HDAC2HDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590340-B1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC (CA) | 2010-04-07 | — | — | EP | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |