Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607664 | 0.91 | IDH1 (0.68) | IDH1EPHX2 | |
| SCHEMBL31616431 | 0.86 | IDH1 (0.63) | IDH1TRPV1EPHX2MEN1NPC1 | |
| SCHEMBL31616378 | 0.86 | IDH1 (0.63) | IDH1TRPV1EPHX2MEN1NPC1 | |
| SCHEMBL31616414 | 0.86 | IDH1 (0.63) | IDH1TRPV1EPHX2MEN1NPC1 | |
| SCHEMBL31616462 | 0.86 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNA | |
| SCHEMBL31616396 | 0.86 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNA | |
| SCHEMBL31616459 | 0.86 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNA | |
| SCHEMBL31616405 | 0.81 | MTOR (0.67) | IDH1TRPV1EPHX2MEN1NPC1 | |
| SCHEMBL31616412 | 0.81 | IDH1 (0.54) | IDH1TRPV1EPHX2MEN1LMNA | |
| SCHEMBL31616384 | 0.81 | IDH1 (0.54) | IDH1TRPV1EPHX2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108187-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2010-09-23 | — | — | WO | disclosed |