Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182225 | 0.91 | IDH1 (0.62) | IDH1EPHX2 | |
| SCHEMBL31616378 | 0.84 | IDH1 (0.63) | IDH1EPHX2SMN1; SMN2 | |
| SCHEMBL31616414 | 0.84 | IDH1 (0.63) | IDH1EPHX2SMN1; SMN2 | |
| SCHEMBL31616431 | 0.84 | IDH1 (0.63) | IDH1EPHX2SMN1; SMN2 | |
| SCHEMBL31616459 | 0.84 | IDH1 (0.69) | IDH1EPHX2 | |
| SCHEMBL31616462 | 0.84 | IDH1 (0.69) | IDH1EPHX2 | |
| SCHEMBL31616396 | 0.84 | IDH1 (0.69) | IDH1EPHX2 | |
| SCHEMBL15702752 | 0.82 | IDH1 (1.00) | IDH1 | |
| SCHEMBL2607661 | 0.81 | IDH1 (0.66) | IDH1EPHX2SMN1; SMN2 | |
| SCHEMBL31616405 | 0.80 | MTOR (0.67) | IDH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099781-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-09 | — | — | US | disclosed |
| US-8969342-B2 | Compounds and methods for treating mammalian gastrointestinal microbial infections | BRANDEIS UNIVERSITY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | University of Georgia Foundation, Inc. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | IMPDH1, IMPDH2, IMPA1 | IDH1 87/4885EPHX2 121/4885SMN1; SMN2 4251/4885 |
| US-20150099781-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | IMPDH1, IMPDH2, IMPA1 | IDH1 87/4885EPHX2 121/4885SMN1; SMN2 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.