Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418504 | 0.87 | — | — | |
| SCHEMBL20179688 | 0.83 | — | — | |
| SCHEMBL45749 | 0.78 | — | — | |
| SCHEMBL1328939 | 0.78 | — | — | |
| SCHEMBL2811646 | 0.75 | — | — | |
| SCHEMBL6895679 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL27415706 | 0.74 | TSHR (0.47) | TSHRTRPA1TDP1 | |
| SCHEMBL2381959 | 0.74 | TSHR (0.47) | TSHRTRPA1TDP1 | |
| SCHEMBL11601251 | 0.74 | — | — | |
| SCHEMBL1017661 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795242-B2 | Methods and compositions for immunomodulation | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2010-09-14 | — | — | US | disclosed |