Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.82 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626735 | 0.90 | KIF11 (1.00) | KIF11CASP3KCNH2MAOB | |
| SCHEMBL3624136 | 0.84 | KIF11 (0.81) | KIF11CASP3KCNH2 | |
| SCHEMBL3620275 | 0.79 | KIF11 (0.79) | KIF11CASP3KCNH2MAOAMAOB | |
| SCHEMBL3624174 | 0.77 | KIF11 (1.00) | KIF11CASP3KCNH2MAOB | |
| SCHEMBL16768161 | 0.77 | KIF11 (0.75) | KIF11CASP3KCNH2 | |
| SCHEMBL3616984 | 0.75 | KIF11 (0.79) | KIF11CASP3KCNH2MAOAMAOB | |
| SCHEMBL3614716 | 0.72 | KIF11 (0.72) | KIF11CASP3KCNH2 | |
| SCHEMBL3616992 | 0.72 | KIF11 (0.72) | KIF11CASP3KCNH2 | |
| SCHEMBL3625650 | 0.72 | KIF11 (1.00) | KIF11CASP3KCNH2MAOAMAOB | |
| SCHEMBL17151556 | 0.72 | KIF11 (1.00) | KIF11CASP3KCNH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110400-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-09-30 | — | — | WO | disclosed |