Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10248260 | 0.83 | MDM2 (0.39) | MDM2TP53PDK2CYP1A2CYP2C19 | |
| SCHEMBL10249558 | 0.82 | MDM2 (0.36) | MDM2TP53LTB4RPDK2CYP1A2 | |
| SCHEMBL9814079 | 0.70 | AOC3 (0.49) | MMP2MMP9MMP12 | |
| SCHEMBL23588163 | 0.69 | AOC3 (0.50) | LMNASMN1; SMN2MMP2MMP9MMP12 | |
| SCHEMBL10249538 | 0.66 | NPC1 (0.45) | LTB4RCYP1A2CYP2C19MAPK1CYP3A4 | |
| SCHEMBL11621719 | 0.65 | AOC3 (0.46) | SMN1; SMN2MMP2MMP9 | |
| SCHEMBL13783741 | 0.64 | CNR1 (0.46) | MMP2 | |
| SCHEMBL13783740 | 0.64 | CNR1 (0.46) | MMP2 | |
| SCHEMBL13783739 | 0.64 | CNR1 (0.46) | MMP2 | |
| SCHEMBL6683963 | 0.64 | AOC3 (0.52) | ALDH1A1LMNASMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010104169-A1 | FLUORENE COMPOUND | 味の素株式会社 (JP) | 2010-09-16 | — | — | WO | disclosed |