SCHEMBL13186237

SCHEMBL13186237

CC(=O)C1CC2CC(C(C)C)C[C@@H](C1)N2C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26492652 0.83 TSHR (0.32)
SCHEMBL15080322 0.83 TSHR (0.32)
SCHEMBL12868770 0.83 TSHR (0.32)
SCHEMBL20756547 0.78 LMNA (0.42) LMNACYP2C9
SCHEMBL15854040 0.71 CYP2C9 (0.52) LMNACYP2C9
SCHEMBL803421 0.71 CYP2C9 (0.52) LMNACYP2C9
SCHEMBL16743566 0.71 CYP2C9 (0.52) LMNACYP2C9
SCHEMBL15468904 0.71 CYP2C9 (0.52) LMNACYP2C9
SCHEMBL12271477 0.71 CYP2C9 (0.52) LMNACYP2C9
SCHEMBL13403910 0.69 SMN1; SMN2 (0.37) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010111136-A2 ALISKIREN MODULATION OF NEUROGENESIS BRAINCELLS, INC. (US) 2010-09-30 WO disclosed