Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26560458 | 0.82 | HTR1D (0.43) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14183094 | 0.79 | MAPK14 (0.48) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14320398 | 0.79 | BACE1 (0.42) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL27962016 | 0.75 | HTR1D (0.40) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7143060 | 0.75 | MAPK14 (0.52) | HTR1DPIK3CDPIK3CAPDE3BPDE3A | |
| SCHEMBL24196019 | 0.75 | HTR1D (0.40) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4772120 | 0.75 | HTR2C (0.46) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17361404 | 0.74 | PIK3CA (0.41) | AAK1HTR1DPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4574087 | 0.74 | MAPK14 (0.46) | HTR1DPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18857842 | 0.74 | MAPK14 (0.47) | HTR1DPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |