Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348825 | 0.88 | KDM4E (0.53) | KDM4EMAPTUCHL1MEN1KMT2A | |
| SCHEMBL345989 | 0.81 | MAPT (0.47) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10154924 | 0.75 | KDM4E (0.44) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL22435184 | 0.72 | MAPT (0.56) | KDM4EMAPTUCHL1MEN1KMT2A | |
| SCHEMBL30028627 | 0.72 | MAPT (0.68) | KDM4EMAPTUCHL1NPSR1ALDH1A1 | |
| SCHEMBL24828267 | 0.71 | MAPT (0.67) | KDM4EMAPTUCHL1MEN1KMT2A | |
| SCHEMBL15075363 | 0.71 | MAPT (0.55) | KDM4EMAPTUCHL1NPSR1CYP1A2 | |
| SCHEMBL9925007 | 0.71 | MAPT (0.54) | KDM4EMAPTUCHL1MEN1KMT2A | |
| SCHEMBL27215188 | 0.71 | MAPT (0.54) | KDM4EMAPTUCHL1NPSR1CYP1A2 | |
| SCHEMBL22412886 | 0.70 | MAPT (0.53) | KDM4EMAPTUCHL1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111060-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |