Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187309 | 0.81 | ALDH1A1 (0.53) | HPGDALDH1A1XDHKDM4EHSD17B10 | |
| SCHEMBL12235799 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1XDHKDM4EHSD17B10 | |
| SCHEMBL12235665 | 0.76 | ALDH1A1 (0.47) | HPGDALDH1A1XDHKDM4EHSD17B10 | |
| SCHEMBL24659286 | 0.73 | PARP1 (0.36) | ALDH1A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL17325898 | 0.71 | ALDH1A1 (0.49) | HPGDALDH1A1XDHKDM4EHSD17B10 | |
| SCHEMBL28798557 | 0.68 | SRC (0.56) | HPGDALDH1A1XDHTSHRSRC | |
| SCHEMBL9503859 | 0.67 | PDPK1 (0.56) | PDPK1ADORA3MGMT | |
| SCHEMBL20180773 | 0.66 | PDPK1 (0.43) | HPGDALDH1A1KDM4EGAASRC | |
| SCHEMBL13981736 | 0.65 | ALDH1A1 (0.63) | HPGDALDH1A1XDHKDM4EHSD17B10 | |
| SCHEMBL18779094 | 0.65 | KDM4E (0.48) | HPGDALDH1A1XDHKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053606-A9 | SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-09-02 | — | — | WO | disclosed |