Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399411 | 0.86 | CA1 (0.64) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL13262741 | 0.86 | CA1 (0.48) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL17478424 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL17478343 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL4119861 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL1338041 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL4101120 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL13263584 | 0.85 | CA1 (0.47) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL17478334 | 0.84 | CA1 (0.46) | CA1CA2ACHEEPHX2MTNR1A | |
| SCHEMBL2629486 | 0.84 | CA1 (0.46) | CA1CA2ACHEEPHX2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010099938-A1 | SULFONYLATED TETRAHYDROAZOLOPYRAZINES AND THEIR USE AS MEDICINAL PRODUCTS | Grünenthal GmbH (DE) | 2010-09-10 | — | — | WO | disclosed |