Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985010 | 0.92 | DGAT1 (0.68) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045616 | 0.92 | DGAT1 (0.64) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL9985440 | 0.90 | DGAT1 (0.72) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045656 | 0.89 | DGAT1 (0.65) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045707 | 0.86 | DGAT1 (0.68) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045658 | 0.86 | DGAT1 (0.62) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL9983922 | 0.84 | DGAT1 (0.57) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL9984767 | 0.83 | DGAT1 (0.73) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045664 | 0.82 | DGAT1 (0.65) | DGAT1CYP2C9TP53THRBMAPT | |
| SCHEMBL12045613 | 0.82 | TP53 (0.53) | DGAT1CYP2C9TP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107765-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |