Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045662 | 0.93 | DGAT1 (0.61) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL9985829 | 0.93 | DGAT1 (0.65) | DGAT1TP53LMNACYP2C9 | |
| SCHEMBL12045621 | 0.87 | DGAT1 (0.63) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL9984513 | 0.87 | DGAT1 (0.67) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL12045657 | 0.87 | DGAT1 (0.64) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL9986009 | 0.86 | DGAT1 (0.66) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL12045660 | 0.79 | TP53 (0.52) | DGAT1TP53LMNACYP2C9MAPT | |
| SCHEMBL9985427 | 0.79 | DGAT1 (0.58) | DGAT1TP53LMNACYP2C9 | |
| SCHEMBL12045707 | 0.79 | DGAT1 (0.68) | DGAT1TP53CYP2C9MAPTTHRB | |
| SCHEMBL12045658 | 0.78 | DGAT1 (0.62) | DGAT1TP53CYP2C9MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107765-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |