Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.57 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189763 | 0.90 | DGAT1 (0.63) | DGAT1SOAT2KDR | |
| SCHEMBL9985077 | 0.87 | DGAT1 (0.75) | DGAT1SOAT2KDR | |
| SCHEMBL12045642 | 0.82 | DGAT1 (0.66) | DGAT1SOAT2KDR | |
| SCHEMBL9984264 | 0.78 | DGAT1 (0.63) | DGAT1SOAT2KDR | |
| SCHEMBL9984398 | 0.77 | DGAT1 (0.82) | DGAT1SOAT2KDR | |
| SCHEMBL9984802 | 0.75 | DGAT1 (0.78) | DGAT1SOAT2KDR | |
| SCHEMBL12045823 | 0.73 | DGAT1 (1.00) | DGAT1SOAT2KDR | |
| SCHEMBL9983795 | 0.73 | DGAT1 (1.00) | DGAT1SOAT2KDR | |
| SCHEMBL9983800 | 0.73 | DGAT1 (1.00) | DGAT1SOAT2KDR | |
| SCHEMBL15445012 | 0.73 | DGAT1 (1.00) | DGAT1SOAT2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107765-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |