Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16503498 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL18028836 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL17258614 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL18028795 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL10371824 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL28258812 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL9570165 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL12482430 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL16509706 | 0.80 | CA1 (0.46) | ALDH1A1KMT2AKDM4EGMNNLMNA | |
| SCHEMBL9598314 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010099786-A1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2010-09-10 | — | — | WO | disclosed |