Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676021 | 0.81 | MAPT (0.72) | MAPTKMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL27280782 | 0.77 | MAPT (0.60) | MAPTKMT2AAPEX1BLMPOLB | |
| SCHEMBL21827346 | 0.77 | MAPT (0.60) | MAPTKMT2AAPEX1BLMPOLB | |
| SCHEMBL24252607 | 0.77 | MAPT (0.60) | MAPTKMT2AAPEX1BLMPOLB | |
| SCHEMBL13189284 | 0.76 | SMN1; SMN2 (0.43) | MAPTKMT2AAPEX1BLMPOLB | |
| SCHEMBL11623232 | 0.74 | APEX1 (0.46) | MAPTKMT2AAPEX1BLMPOLB | |
| SCHEMBL11103604 | 0.70 | DPP4 (0.44) | MAPTRAB9A | |
| SCHEMBL9739887 | 0.70 | DPP4 (0.44) | MAPTRAB9A | |
| SCHEMBL21878237 | 0.69 | MAPT (0.42) | MAPTKMT2ARAB9APOLB | |
| SCHEMBL21878234 | 0.69 | MAPT (0.42) | MAPTKMT2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106441-A2 | PEPTIDOMIMETICS FOR MODULATING INTERLEUKIN-1 RECEPTOR | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2010-09-23 | — | — | WO | disclosed |