Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.78 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.55 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262233 | 0.89 | DGAT1 (0.85) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL10197338 | 0.88 | DGAT1 (0.87) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL407907 | 0.88 | DGAT1 (1.00) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL10197249 | 0.88 | DGAT1 (1.00) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL13190495 | 0.88 | DGAT1 (0.62) | DGAT1SOAT2SOAT1 | |
| SCHEMBL13190400 | 0.88 | DGAT1 (0.83) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL407906 | 0.88 | DGAT1 (1.00) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL10197240 | 0.88 | DGAT1 (1.00) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL10197313 | 0.87 | DGAT1 (0.82) | DGAT1SOAT2CYP2C9SOAT1DGAT2 | |
| SCHEMBL13190626 | 0.87 | DGAT1 (0.63) | DGAT1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107768-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |