Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479544 | 0.80 | DHODH (0.57) | DHODHMAPTGFERNGLY1FABP4 | |
| SCHEMBL8171612 | 0.80 | DHODH (0.57) | DHODHMAPTGFERNGLY1FABP4 | |
| SCHEMBL29417549 | 0.76 | DHODH (0.53) | DHODHMAPTGFERNGLY1FABP4 | |
| SCHEMBL30721208 | 0.76 | DHODH (0.53) | DHODHMAPTGFERNGLY1MEN1 | |
| SCHEMBL12984259 | 0.76 | DHODH (0.53) | DHODHMAPTGFERNGLY1MEN1 | |
| SCHEMBL29417536 | 0.73 | DHODH (0.52) | DHODHMAPTMEN1KMT2ARAB9A | |
| SCHEMBL479877 | 0.72 | DHODH (1.00) | DHODHMAPTMEN1KMT2ARAB9A | |
| SCHEMBL17366074 | 0.71 | DHODH (0.47) | DHODHMAPTGFERNGLY1FABP4 | |
| SCHEMBL27990835 | 0.71 | BCL6 (0.60) | DHODHMAPTGFERNGLY1SMN1; SMN2 | |
| SCHEMBL28461914 | 0.70 | CYP1A2 (0.44) | RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010109123-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-30 | — | — | WO | disclosed |