Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417555 | 0.88 | MAPT (0.52) | DHODHKMT2AMEN1HTTRAB9A | |
| SCHEMBL28978820 | 0.88 | MAPT (0.52) | DHODHKMT2AMEN1HTTRAB9A | |
| SCHEMBL13730480 | 0.78 | RPS27 (0.46) | KMT2AMEN1HTTRAB9ANPSR1 | |
| SCHEMBL8171612 | 0.76 | DHODH (0.57) | DHODHKMT2AMEN1HTTRAB9A | |
| SCHEMBL13730216 | 0.76 | MAOA (0.57) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1312979 | 0.74 | POLB (0.57) | KMT2AMEN1HTTRAB9ANPC1 | |
| SCHEMBL13190366 | 0.73 | DHODH (0.57) | DHODHKMT2AMEN1HTTRAB9A | |
| SCHEMBL479544 | 0.73 | DHODH (0.57) | DHODHKMT2AMEN1HTTRAB9A | |
| SCHEMBL1680784 | 0.73 | MAPT (0.50) | RAB9ANPC1ALDH1A1MAPK8MAPT | |
| SCHEMBL4299384 | 0.73 | MAPT (0.50) | KMT2AMEN1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |