Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190833 | 0.76 | — | — | |
| SCHEMBL10102740 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KMT2AATMMAPTHTT | |
| SCHEMBL10102722 | 0.66 | MAPT (0.36) | ALDH1A1KMT2AATMKDM4ECYP2C19 | |
| SCHEMBL11902276 | 0.65 | MAPT (0.36) | ALDH1A1KMT2AATMCYP2C19MAPT | |
| SCHEMBL10102780 | 0.64 | ALDH1A1 (0.39) | ALDH1A1KMT2AATMKDM4ECYP2C19 | |
| SCHEMBL11864925 | 0.63 | ATM (0.36) | ALDH1A1KMT2AATMKDM4ECYP2C19 | |
| SCHEMBL10102723 | 0.63 | ATM (0.33) | ALDH1A1KMT2AATMKDM4ECYP2C19 | |
| SCHEMBL10102711 | 0.63 | ALDH1A1 (0.44) | ALDH1A1KMT2AATMKDM4EMAPT | |
| SCHEMBL10102725 | 0.63 | GAA (0.34) | ALDH1A1KMT2AKDM4EMAPTHTT | |
| SCHEMBL867642 | 0.63 | KMT2A (0.41) | ALDH1A1KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010104406-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-09-16 | — | — | WO | disclosed |