Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13001465 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL7557473 | 0.79 | ATM (0.56) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL10102691 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL868820 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL19125013 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL31466953 | 0.77 | GAA (0.58) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL27849205 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1MAPTHTTLMNA | |
| Bromide SCHEMBL31316350 | 0.75 | GAA (0.57) | KDM4EALDH1A1MAPTHTTLMNA | |
| Bromide SCHEMBL28466495 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL9669528 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010104406-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-09-16 | — | — | WO | disclosed |