Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192773 | 0.89 | POLB (0.47) | CCR6PAX8POLBABCB1MEN1 | |
| SCHEMBL3968828 | 0.87 | CCR6 (0.54) | CCR6PAX8ABCB1KMT2AALDH1A1 | |
| SCHEMBL25448884 | 0.85 | CCR6 (0.52) | CCR6PAX8ABCB1ALDH1A1TSHR | |
| SCHEMBL25448882 | 0.84 | CCR6 (0.51) | CCR6PAX8ABCB1ALDH1A1KDM4E | |
| SCHEMBL18745410 | 0.82 | MEN1 (0.43) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12747675 | 0.80 | POLB (0.45) | CCR6PAX8POLBMEN1KMT2A | |
| SCHEMBL9547229 | 0.79 | POLB (0.46) | CCR6PAX8POLBMEN1KMT2A | |
| SCHEMBL31629174 | 0.78 | CCR6 (0.62) | CCR6PAX8KMT2AALDH1A1LMNA | |
| SCHEMBL27374010 | 0.78 | CCR6 (0.48) | CCR6PAX8POLBMEN1KMT2A | |
| SCHEMBL10478127 | 0.78 | ABCB1 (0.53) | CCR6PAX8ABCB1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |
| US-20140045833-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| WO-2012135944-A9 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2014-01-09 | — | — | WO | disclosed |
| WO-2012135944-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045833-A1 | Protein Kinase Inhibitors | LCK, BTK, TEC | CCR6 650/4885PAX8 3675/4885POLB 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.