Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192773 | 0.85 | POLB (0.47) | POLBCCR6PAX8ALDH1A1MEN1 | |
| SCHEMBL12747675 | 0.83 | POLB (0.45) | POLBCCR6PAX8ALDH1A1MEN1 | |
| SCHEMBL27374010 | 0.79 | CCR6 (0.48) | POLBCCR6PAX8ALDH1A1MEN1 | |
| SCHEMBL13192604 | 0.79 | CCR6 (0.48) | POLBCCR6PAX8ALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL7411923 | 0.77 | CCR6 (0.43) | CCR6PAX8ALDH1A1MEN1KMT2A | |
| SCHEMBL7880329 | 0.76 | ALDH1A1 (0.45) | CCR6PAX8ALDH1A1KMT2A | |
| SCHEMBL21012250 | 0.73 | CCR6 (0.54) | CCR6PAX8ALDH1A1TSHRCYP3A4 | |
| SCHEMBL5331588 | 0.73 | ALDH1A1 (0.51) | CCR6PAX8ALDH1A1KMT2A | |
| SCHEMBL7419081 | 0.72 | SYK (0.48) | POLBCCR6PAX8MEN1KMT2A | |
| SCHEMBL8280919 | 0.72 | ALDH1A1 (0.51) | CCR6PAX8ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |