SCHEMBL131935

SCHEMBL131935

CO[Si](CNCCN)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.43
CA6 P23280 5/20 0.43
CA7 P43166 5/20 0.43
CA9 Q16790 5/20 0.43
CA14 Q9ULX7 5/20 0.43
CA5B Q9Y2D0 5/20 0.43
MEN1 O00255 2/20 0.43
RECQL P46063 2/20 0.43
KMT2A Q03164 2/20 0.43
CA2 P00918 4/20 0.41
CA4 P22748 4/20 0.41
CA5A P35218 4/20 0.41
CA3 P07451 3/20 0.41
ALOX15 P16050 3/20 0.41
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CA1 P00915 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27825483 0.95 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL8380350 0.91 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL137955 0.87 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL14015581 0.87 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL9516038 0.87 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL1104519 0.79
SCHEMBL12190380 0.79 MEN1 (0.30) CA12CA6CA7CA9CA14
SCHEMBL975755 0.78 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL615248 0.78 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL555645 0.78 TSHR (0.46) CA12CA7CA14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110745835-B Preparation method of silicon dioxide/graphene composite aerogel and composite aerogel obtained by preparation method 江苏和硅纳米科技有限公司 2021-04-16 CN claimed
EP-3212292-B1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS OREAL (FR) 2021-01-20 EP claimed
CN-110745835-A Preparation method of silicon dioxide/graphene composite aerogel and composite aerogel obtained by preparation method 福建六树网络科技有限公司 2020-02-04 CN claimed
EP-3298085-B1 WATER-BASED ZINC-RICH PRE-CONSTRUCTION PRIMER SHERWIN WILLIAMS CO (US) 2019-03-27 EP claimed
EP-3081612-B1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO LTD (JP) 2018-11-14 EP claimed
US-20170335066-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS L'OREAL (FR) 2017-11-23 US claimed
EP-3212292-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS L'OREAL (FR) 2017-09-06 EP claimed
CN-104159958-B One-component contact adhesives with improved stability SIKA技术股份公司 2017-03-29 CN claimed
US-9528179-B2 Treatment of steel surfaces WACKER CHEMIE AG (DE) 2016-12-27 US claimed
US-20160340514-A1 WATER-BASED ZINC-RICH PRE-CONSTRUCTION PRIMER THE SHERWIN-WILLIAMS COMPANY (US) 2016-11-24 US claimed
US-5468317-A Glass, epoxy- or amino-silane THE DOW CHEMICAL COMPANY (US) 1995-11-21 US claimed
US-5466727-A Primer composition for improving the bonding of a urethane adhesive to non-porous substrates ESSEX SPECIALTY PRODUCTS, INC. (US) 1995-11-14 US claimed
EP-0498442-B1 Coating thickeners SHERWIN WILLIAMS CO (US) 1995-10-25 EP claimed
WO-1994029390-A1 PRIMER COMPOSITION FOR IMPROVING THE BONDING OF A URETHANE ADHESIVE TO NON-POROUS SUBSTRATES ESSEX SPECIALTY PRODUCTS, INC. (US) 1994-12-22 WO claimed
US-5252668-A Modified with an aminosilane; excellent adhesion and heat resistance SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1993-10-12 US claimed
EP-0498442-A1 Coating thickeners THE SHERWIN-WILLIAMS COMPANY (US) 1992-08-12 EP claimed
US-5041481-A Curable composition comprising adhesion improver SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1991-08-20 US claimed
US-4981987-A Adhesion-improver SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1991-01-01 US claimed
US-4642011-A ORGANIC SILICON COMPOUND HAVING AMINOALKYL GROUP AND ALKOXY GROUP, AND OXIRANE COMPOUND Toacosei Chemical Industry Co., Ltd. (JP) 1987-02-10 US claimed
US-4317123-A Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1982-02-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170335066-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS KRT18, DSG1, KRTCAP2 CA12 1154/4885CA6 1056/4885CA7 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.