Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779905 | 0.97 | CNR2 (0.65) | CNR2ALDH1A1LMNASCN9ATSHR | |
| SCHEMBL13196520 | 0.87 | CNR2 (0.46) | CNR2ALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL2780330 | 0.86 | CNR2 (0.64) | CNR2ALDH1A1LMNASMN1; SMN2SCN9A | |
| SCHEMBL13196498 | 0.84 | CNR2 (0.70) | CNR2ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL2781915 | 0.80 | CNR2 (0.65) | CNR2ALDH1A1TSHRL3MBTL1ANPEP | |
| SCHEMBL2781227 | 0.80 | CNR2 (0.67) | CNR2ALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL2780580 | 0.80 | CNR2 (0.65) | CNR2ALDH1A1LMNAPKMTSHR | |
| SCHEMBL2821973 | 0.79 | CNR2 (0.64) | CNR2PKML3MBTL1ANPEPPOLB | |
| SCHEMBL2781067 | 0.79 | CNR2 (0.69) | CNR2ALDH1A1PKML3MBTL1ANPEP | |
| SCHEMBL2780219 | 0.79 | CNR2 (0.69) | CNR2ALDH1A1PKMTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |