Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.69 |
| ▸ | ANPEP | P15144 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196498 | 0.91 | CNR2 (0.70) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2781801 | 0.90 | CNR2 (0.65) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2782113 | 0.90 | CNR2 (0.72) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2781067 | 0.90 | CNR2 (0.69) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL13196470 | 0.88 | CNR2 (0.61) | CNR2ANPEPPOLBALDH1A1HDAC1 | |
| SCHEMBL2781046 | 0.87 | CNR2 (0.68) | CNR2ANPEPPOLBL3MBTL1HDAC1 | |
| SCHEMBL2780330 | 0.86 | CNR2 (0.64) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2781915 | 0.86 | CNR2 (0.65) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2780013 | 0.85 | CNR2 (0.68) | CNR2ANPEPPOLBALDH1A1L3MBTL1 | |
| SCHEMBL13274022 | 0.85 | CNR2 (0.74) | CNR2ANPEPPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |