Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980734 | 0.87 | MAPT (0.77) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11509889 | 0.83 | MAPT (0.71) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL25280266 | 0.81 | MAPT (0.68) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7160030 | 0.81 | MAPT (0.68) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL802037 | 0.81 | MAPT (1.00) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30301294 | 0.81 | MAPT (1.00) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL24274961 | 0.81 | MAPT (0.68) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5713631 | 0.80 | MAPT (0.82) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4305242 | 0.80 | MAPT (0.67) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27597921 | 0.80 | MAPT (0.67) | MAPTHPGDSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096295-A2 | OXAZOLINE AND/OR OXAZINE COMPOSITIONS | HENKEL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2008156443-A1 | BENZOXAZINE CONTAINING COMPOSITIONS OF MATTER AND CURABLE COMPOSITIONS MADE THEREWITH | HENKEL CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |