Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155775 | 0.86 | MAPT (0.61) | MAPTHPGDMAOBALBNOX4 | |
| SCHEMBL5713564 | 0.86 | MAPT (0.61) | MAPTHPGDMAOBALBNOX4 | |
| SCHEMBL883964 | 0.86 | MAPT (0.75) | MAPTHPGDMAOBALBNOX4 | |
| SCHEMBL27500978 | 0.86 | MAPT (0.61) | MAPTHPGDMAOBALBNOX4 | |
| SCHEMBL5713573 | 0.83 | TUBB4A (0.61) | MAPTHPGDNOX4EGFRMEN1 | |
| SCHEMBL11593766 | 0.82 | MAPT (0.81) | MAPTHPGDNOX4EGFRMEN1 | |
| SCHEMBL5713517 | 0.81 | TUBB4A (0.58) | MAPTHPGDMAOBMEN1HTT | |
| SCHEMBL30301294 | 0.81 | MAPT (1.00) | MAPTHPGDMAOBNOX4EGFR | |
| SCHEMBL802037 | 0.81 | MAPT (1.00) | MAPTHPGDMAOBNOX4EGFR | |
| SCHEMBL5713679 | 0.80 | MAPT (0.55) | MAPTHPGDMAOBALBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251822-A4 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2006-05-31 | — | — | EP | disclosed |
| CN-1196464-C | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2005-04-13 | — | — | CN | disclosed |
| US-6540793-B1 | Coupler for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2003-04-01 | — | — | US | disclosed |
| CN-1396819-A | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2003-02-12 | — | — | CN | disclosed |
| EP-1251822-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | Clairol Incorporated (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001056538-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-09 | — | — | WO | disclosed |